1241. Hepatitis C Cascade of Care in a Multidisciplinary Substance Use Bridge Clinic Model

Abstract Background Hepatitis C virus (HCV) infection is common among persons who inject drugs. Treating HCV in patients present for treatment of substance use disorder (SUD) an opportunity to improve linkage and retention care. The Vanderbilt University Medical Center (VUMC) Bridge Clinic serves a unique patient population that includes individuals with opioid recently presented VUMC complications related use. These are treated by multidisciplinary team addiction agonist therapy as well comorbid medical conditions. aim this study further characterize the cascade care (CoC) bridge clinic setting identify barriers treatment. Methods We performed single-center, ambispective cohort enrolled from 7/1/20 through 6/30/21. Data collection was continued 12/31/21. All were reviewed, active monitored initial evaluation sustained virologic response (measured at least 12 weeks after completing (SVR12). Descriptive statistics including demographics progression CoC presented. Results Characteristics 230 screened reflected Table 1. Figure Of these patients, 96 (42%) had detectable measured blood RNA. 39 (40%) approved treatment, 33 (34%) initiated 25 (26%) completed 13 (14%) achieved SVR12 laboratory confirmation. largest number did not progress those treatment; most reasons loss follow-up or incomplete workup. majority received part their plan. Conclusion This demonstrates opportunities challenges treating SUD model. Ongoing efforts should focus on strategies keep engaged throughout Disclosures David Marcovitz, MD, Better Life Partners LLC: Stocks/Bonds|Silver Pines Stocks/Bonds.